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 Volume 1, Issue 1, Jan 2013
 Volume 1, Issue 1, Jan 2013
 Volume 1, Issue 1, Jan 2013
 Volume 1, Issue 1, Jan 2013
 Volume 1, Issue 1, Jan 2013
 Volume 1, Issue 1, Jan 2013
 Volume 1, Issue 1, Jan 2013

Volume 1, Issue 2, February 2013

International Journal of Advance Research in Biology & Pharmacy Research (IJOARBP)

The viability of transgenesis for control of malaria[ ]

Malaria is a serious problem and a reason for severe mortality especially in developing countries. Several techniques such as insecticides, drugs, sterile insect technique, etc. have been employed by researchers to eradicate the lethal disease. However, the parasites and vectors gained significant immunity against the treatment. Incorporation of genetically modified vectors (GMVs) into disease control could be promising. Genetic modification (GM) of mosquitoes offers opportunities for controlling malaria. Transgenic strains of mosquitoes have been developed and evaluation of these to 1) replace or suppress wild vector populations and 2) reduce transmission and deliver public health gains are an imminent prospect. Identification of promoters, effectors, and reporter genes affecting malaria in mice further developed hopes for this process. This review focuses on malaria and the use of transgenesis for its prevention and cure, along with highlighting the associated challenges. Unlike other current therapies, there are no precedents (yet) of successful transgenesis application, leading to the classification of this strategy as linear technology-push, but researchers are optimistic that these strategies could be further improved.

Evidence for cure of flu through nose breathing[ ]

Breathing through nose is a healthy habit approved by researchers and it is also helpful in cure of flu. Because normal nose breathing help us to use nitric oxide generated in our sinuses. And research told us that nitric oxide has confirmed function of destruction of viruses, parasitic organisms, and malignant cells in the airways and lungs by inactivating their respiratory chain enzymes. NO inhibits the replication of influenza viruses, probably during the early steps of the viruses�f replication cycle, involving the synthesis of vRNA and mRNA encoding viral proteins. Thus NO is responsible for the cure of flu by killing influenza virus.

Biodiversity Of Cyno-bacteria In Soils Of Greater Haflong And Their Nitrogen Fixing Capacity[ ]

Occurrence of blue-green algae in plain land, pond side, hilly area and dry rice field soils of Greater Haflong and N2 fixation of some of them have been studied. Twenty four (24) species under 20 genera were identified and their number varied from 0.11�~104/g to 2.8�~104/g soil. Anabaena oryzae, Calothrix sp., Cylindrospermum majus and Hapalosiphon hibernicus and Nostoc spongiaeforme were selected for their nitrogen fixing potential. Maximum amount of total nitrogen was recorded in Nostoc spongiaeforme followed by Hapalosiphon hibernicus, Cylindrospermum majus, Anabaena oryzae and Calothrix sp. after 30 days growth in batch cultures.

Evaluation of alteration of serum total bilirubin, Gamma Glutamyl transferase (GGT), Blood Urea Nitrogen (BUN), serum creatinine as potential markers of Kidney function in Hepatitis C infected individuals[ ]

The objective of present study is to evaluate the alternation in serum total bilirubin, Gamma glutamyl transferase, blood urea nitrogen, serum creatinine levels in patients suffering from HCV. The approach is to see the effect of Hepatitis C on kidneys. Design of study: These tests were performed on 25 individuals with confirm HCV by ELISA. These tests were also performed on 25 normal healthy individuals for the purpose of comparison. Setting: Institute of Molecular biology and Biotechnology, The University of Lahore, Raiwund, Lahore. Samples were collected from Shaukat Khanum Memorial Cancer Hospital and Research Centre. Material and methods: Patients suffering from HCV were included in the present study. Diabetic patients, patient suffering from blood cancer, patient suffering from renal failure, patient suffering from Hypertension, patient suffering from cardiac disease, patient suffering from HCV plus any other disorder were excluded from the present study to evaluate the biochemical alteration in serum total bilirubin, Gamma GT, BUN, serum creatinine in patients suffering from HCV. Statistical analysis: Statistical analysis was performed using the statistical package for social studies (SPSS) version 16 for windows.

In-vivo assay of Antidiarrhoeal, Antidiabetic and in-vitro assay of Antimicrobial, Antioxidant activity of the methanolic extract of the leaves of Clerodendrum viscosum Vent[ ]

The present study was aimed to investigate the possible Antidiarrhoeal, Antidiadetic Antioxidant and Antibacterial activity of methanolic extracts of leaves of Clerodendrum viscosum Vent. This study was conducted to evaluate the Antibacterial activity of methanolic extracts from leaves of Clerodendrum viscosum vent using disc diffusion method. Standard antibiotic disc of kanamycin (30μg/disc) for bacterial species were used as standard. In this Antibacterial screening, the crude extracts were used at a concentration 500 μg/disc. None of the microorganisms were remarkably susceptible to the extract. For Antidiabetic study in vivo model was utilized.


The pollutants and drastic environmental variation have also adversely effected and changed water qualities i.e. colour, hardness, turbidity , alkalinity, pH. COD, BOD and TDS etc. Aquatic life, thus , also is affected. Changes in morphology of fish like- colour, pigmentation, length, weight mass, structure of scales, finrays etc. may occur. This can not be ignored that the afore-mention variation may be responsible to develop new varieties or sub species. Unfortunately, negligible work is done in relation to fish fauna of the area in recent-past. Though, appreciable limnological work is done, yet the fish fauna remained unexplored. The fauna study is of tremendous significance in determining population density and calculating sub specific diversity and conservation of ecosystem in Damoh District.


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